Peter Attia on the INSANE Longevity Benefits of Low ApoB (how to lower ApoB with diet)

Comments · 1.1K

• FO

  @FoundMyFitnessClips · 2 years ago · pinned

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• GA

  @gabymalembe · 2 years ago

  Having perfectionist tendencies reduces life expectancy by 7 to 9 years.

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• MD

  @md82892 · 2 years ago

  Here are some key bullet points and suggestions from the video: <br> <br>- ApoB levels rise with age likely due to decreased LDL receptor clearance, not increased synthesis. Evolutionarily we make more than needed. <br> <br>- Reference ranges for ApoB are based on population distributions, not health risk. We should ignore these. <br> <br>- ApoB is causally linked to atherosclerosis. Like smoking and lung cancer, it should be eliminated entirely rather than managed. <br> <br>- Children have ApoB levels below 20 mg/dL, showing low levels are safe and physiologic. Levels below 30 mg/dL may halt atherosclerosis. <br> <br>- Consider lifetime ApoB exposure (&quot;area under the curve&quot;), not just current levels. Lower for longer is best. <br> <br>- Other major causal CVD factors are insulin resistance, hypertension, smoking. Control those too. <br> <br>- To lower ApoB through diet: <br> <br>- Reduce insulin resistance by limiting carbohydrates, especially refined/starchy carbs <br> <br>- Limit saturated fat quantity, as it increases cholesterol synthesis and reduces LDL receptors <br> <br>- Individual response varies; monitor lipids on high fat diets. Avoid if ApoB/LDL increase markedly. <br> <br>Suggestions: <br> <br>- Get an ApoB test and aim for level below 30 mg/dL through diet and medication if needed <br> <br>- Adopt very low carb diet to improve insulin sensitivity <br> <br>- Limit saturated fat intake if needed to control ApoB levels <br> <br>- Exercise, maintain normal BMI, don&apos;t smoke to control other CVD risk factors <br> <br>- Re-test ApoB every 3-6 months and adjust diet/meds to keep levels very low lifelong

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• GR

  @Grrrnthumb · 11 months ago

  If you&apos;re here, you&apos;ll be interested to know that this study found a 23% reduction in ApoB in 24 weeks on a diet high in fish: <br>&quot;Effects of Therapeutic Lifestyle Change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects&quot;

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• WI

  @willseely4515 · 2 years ago

  I&apos;ve been bugging my cardiologist &nbsp;about a ApoB test for 2 years. &quot;We don&apos;t do that&quot; is their response. I&apos;ve been sandbagged by doctors my whole 62 year life.

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• VI

  @VietYork · 2 years ago

  summary by Molly.cơm <br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=3">00:03</a> ApoB reference ranges are population-based and don&apos;t reflect true risk levels<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=137">02:17</a> Eliminate causal factors for disease as soon as possible<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=270">04:30</a> Lowering ApoB may reduce the risk of atherosclerosis.<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=412">06:52</a> Aging process primarily impacts clearance level of ApoB.<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=531">08:51</a> Evolutionary prioritization of cholesterol production leads to high levels, but modern environment no longer requires it.<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=660">11:00</a> Maintaining ApoB level below 30 mg/dL may prevent atherosclerosis.<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=788">13:08</a> Maintaining low ApoB levels is crucial for longevity and health.<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=922">15:22</a> Lowering triglyceride levels is key to managing ApoB<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=1048">17:28</a> Carbohydrate restriction is most effective for triglyceride reduction<br><a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=1174">19:34</a> Various individuals react differently to low carb, high fat diets.

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• PA

  @pathologicaldoubt · 2 years ago

  Misrepresented but overly relied on bio marker reference ranges is a widespread issue that deserves more attention

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• EN

  @EnglishVibes331 · 1 month ago (edited)

  This is how &nbsp;I approach my positive CAC score - reduce or &nbsp;eliminate all risky behaviors . &nbsp;My ApoB is now 32. I’m more focused on insulin and glucose now as well as inflammation (hs-CRP is 0.3).

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• SH

  @sharonsteedly1950 · 2 years ago

  My recent ApoB was the first one my clinician has ever ordered. They had to call a tech to add the test to their system. Hopefully, my requesting the test and being persistent will open accessibility for others in my community and help educate my Healthcare provider

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• MR

  @MrBrianDuga · 2 years ago (edited)

  The contextual citing of literature on this channel is an excellent feature- thank you

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• ED

  @editsbyjsg · 2 years ago

  <a href="https://www.youtube.com/watch?v=-OxvLbjMP_o&amp;t=920">15:20</a> - He gets to it

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• CL

  @clarefritsch6550 · 2 years ago

  Great You Tube presentation. Reminds me of when Peter and Rhonda started putting out podcasts 4-5 years ago. Solid foundational information. Thank you!

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