Cancer Is a Metabolic Disease — Here’s How to Starve It | Dr. Dominic D’Agostino

Comments · 316

• JE

  @JesseChappus · 3 years ago · pinned

  Thank you for watching this episode with Dr. Dominic D'Agostino! If you're finding it valuable, please vote by hitting the LIKE button on the video. This lets me know what type of guests to book for upcoming shows. Thanks! -Jesse 💙

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• MS

  @msvergara · 3 years ago

  my 80 years old brother was diagnosis with adenocarcinoma in the pancreas en of march 2023, I put him on keto/low carbs/intermitent fastning, turmeric, berberine and other supplements I have been reading about. by end of July the cancer was gone. I am graduated md, so I understand the logic and how to implement the treatment

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• LT

  @LTPottenger · 3 years ago (edited)

  Great to see how the news about fasting and low carb for cancer prevention and mitigation is spreading! Some benefits of doing occasional extended fasting: High blood pressure is lowered to normal levels very quickly while fasting. <br>Fasting restores NAD+ to healthy levels.<br><br>Vitamin D plasma levels are increased as fasting improves metabolic health, and vitamin D in turn increases autophagy.<br><br>Fasting stimulates phagocytosis, the ingestion of bacteria, plaques and viruses by the immune system. It will also remove any &apos;foreign material&apos; like spikes that are not supposed to be there. Whether natural or unnatural in origin..<br><br>Fibrosis/scarring is reversed over time.<br><br>Fasting increases nitric oxide release. <br><br>Telomeres are lengthened and fasting also increases anti-aging Yamanaka factors.<br><br>Blood clotting is reduced and blood clots and arterial plaque are reabsorbed into the body. <br><br>Fasts from 36-96 h increase metabolic rate due to norepinephrine release! <br><br>After 72 hours or more fasted, your body recycles up to 1/3 of all immune bodies, rejuvenating your entire immune system. This helps prevent the onset of new autoimmune conditions, which develop through a leaky gut and damaged immune system.<br><br>Fasting can help with MS, Depression, BPD, Autism and seizures.<br><br>Thymus is regenerated, which suppresses aging and renews the immune system. The thymus also plays a vital role in fighting cancer.<br><br>Blood sugar and insulin are lowered when fasting, allowing white blood cells to move more freely throughout the body and do their job.<br><br>Weight loss from daily caloric restriction has 1/4 to 1/3 of the weight lost as lean tissue while many studies show fat loss from 36 h fasts without losing any lean tissue! <br><br>The obese will lose extra tissue like loose skin while fasting, but the skinny or frail will have increased growth hormone release than the obese, which helps to make more lean tissue and reduce frailness.<br><br>The hunger hormone ghrelin also lowers with extended fasting and rises from dieting. <br><br>When you move out of MTOR your body shuts down the building blocks of the cell required for viruses to replicate.<br><br>What breaks a fast? Anything with protein or carbohydrates in it will break a fast. Most teas and herbs are OK. Most supplements and meds will either break ketosis directly or contain a filler that will. Many meds are dangerous to take while fasting.<br><br>Does fasting lower testosterone? No, it raises it when the fast is broken by increasing lutenizing hormone. Fasting also increases insulin sensitivity, which helps with muscle building.<br><br>Fasts of 36-96 will not affect short term female fertility or affect menstrual cycle. They also may increase long term fertility, especially in women with PCOS.<br><br>Fasting reduces pain and anxiety by stimulating the endocannabinoid system in a similar way to CBD oil.<br><br>Fasting very quickly reduces leptin resistance, which impairs immune function. One day of fasting can cut your leptin levels in half and gets your immune system working properly again!<br><br>Stomach acid is reduced over time while fasting and can allow for the healing of treatment resistant ulcers. Some patients may need continued acid reduction medication while fasting.<br><br>Does the body preferentially prefer glucose as a fuel? No. Except for brief periods of very intense exercise, your body mainly burns fats in the form of free fatty acids. Your brain also prefers to burn ketones at a rate of around 2.5 to 1 when they are available in equal quantity to glucose.<br><br>Fasting stimulates the AMPK complex and activates autophagy. Autophagy (literally self eating) will cause cells to recycle foreign matter such as viruses and kill cancerous and senescent cells<br><br>Lowering insulin via fasting virtually eliminates chronic inflammation in the body. <br><br>It increases mitochondrial function and repairs mitichondrial DNA, leading to improved ATP production and oxygen efficiency. Increased mitochondrial function also has the added benefit of increasing your metabolism, fighting infection and cancer prevention!<br><br>Fasting releases BDNF and NGF in the blood which stimulates new nerve and brain cell growth. This can help a great deal with diseases like MS, peripheral neuropathy and Alzheimers.<br><br>When not in ketosis, the brain can only burn carbohydrate, which produces a great deal of damaging ROS the brain has to deal with.<br><br>Fasting also increases telomere length, negating some of the effects of aging at a cellular level.<br><br>When you fast, this stimulates apoptosis in senescent or genetically damaged cells, destroying them.<br><br>A fasting mimicking diet for 3-5 days in a row also provides many of the same benefits as water fasting. FMD usually has 200-800 calories, under 18 g of protein and extremely low carbs.<br><br>Exogenous ketones can aid with fasting, making it easier in healthy people and allowing some people with specific issues to fast in spite of them without worrying as much about hypoglycemia.<br><br>Children, pregnant or nursing women should not fast for periods longer than 16 hours. People with pancreatic tumors or certain forms of hypoglycemia generally cannot fast at all. Type 1 diabetics can also fast but it is more complicated and should be approached with caution as it could lead to ketoacidosis. If you experience extreme symptoms of some kind, especially dizziness or tremors, then simply break the fast and seek advice.<br><br>Resources:<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141719/<br>https://pubmed.ncbi.nlm.nih.gov/2518860/<br>https://pubmed.ncbi.nlm.nih.gov/29727683/<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470960/<br>https://pubmed.ncbi.nlm.nih.gov/25909219/<br>https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30605-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276518306051%3Fshowall%3Dtrue<br>https://pubmed.ncbi.nlm.nih.gov/28235195/<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/<br>https://www.nia.nih.gov/news/research-intermittent-fasting-shows-health-benefits<br>https://medicalxpress.com/news/2022-10-treatment-pulmonary-fibrosis-focus-telomeres.html<br>https://www.ncbi.nlm.nih.gov/pubmed/10859646<br>https://academic.oup.com/ajcn/article/81/1/69/4607679<br>https://www.amjmedsci.org/article/S0002-9629%2815%2900027-0/fulltext<br>https://europepmc.org/article/MED/22402737?javascript_support=no<br>https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2265.2005.02288.x<br>https://www.nejm.org/doi/full/10.1056/NEJMoa012908<br>https://www.collective-evolution.com/2017/05/16/study-shows-how-fasting-for-3-days-can-regenerate-your-entire-immune-system/<br>https://pubmed.ncbi.nlm.nih.gov/7714088/<br>https://www.cell.com/cell/fulltext/S0092-8674(19)30849-9<br>https://pubmed.ncbi.nlm.nih.gov/27569118/<br>https://www.sciencedirect.com/science/article/pii/S1931312809002832<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413655/<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/<br>https://www.arcjournals.org/pdfs/ijrsb/v3-i11/7.pdf<br>https://www.ncbi.nlm.nih.gov/pubmed/25686106<br>https://pubmed.ncbi.nlm.nih.gov/21410865/<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607739/<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017674/<br>https://pubmed.ncbi.nlm.nih.gov/23408502/<br>https://pubmed.ncbi.nlm.nih.gov/20921964/<br>http://www.sciencedirect.com/science/article/pii/S0005272806000223<br>https://pubmed.ncbi.nlm.nih.gov/6859089/<br>https://www.ncbi.nlm.nih.gov/pubmed/10232622<br>https://www.clinicaltrials.gov/ct2/show/NCT04375657<br>https://pubmed.ncbi.nlm.nih.gov/31877297/<br>https://n.neurology.org/content/88/16_Supplement/P3.090<br>https://pubmed.ncbi.nlm.nih.gov/31890243/<br><br>https://www.ncbi.nlm.nih.gov/gene/25712<br>https://pubmed.ncbi.nlm.nih.gov/23707514/<br>https://www.ncbi.nlm.nih.gov/pubmed/24905167<br>https://www.health.harvard.edu/heart-health/abundance-of-fructose-not-good-for-the-liver-heart<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093158/<br>https://clinical.diabetesjournals.org/content/36/3/217<br>https://www.ncbi.nlm.nih.gov/pubmed/23876457<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407435/<br>https://pubmed.ncbi.nlm.nih.gov/15522942/<br>https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2019.33.1_supplement.819.10<br>https://www.biorxiv.org/node/93305.full<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895342/<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526871/<br>http://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00224-7<br>https://repository.upenn.edu/cgi/viewcontent.cgi?article=1537&amp;context=edissertations<br>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779438/<br>https://www.nejm.org/doi/full/10.1056/NEJMc2001176<br>https://pubmed.ncbi.nlm.nih.gov/20102774/<br><br>This list compiled over years of research by the user known as Pottenger&apos;s Human on youtube but feel free to copy and paste this anywhere you like, no accreditation needed!<br><br>My channel will always contain an updated version of this list of fasting benefits on the community tab. I also have playlists on fasting and health topics.

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• CA

  @catcan221 · 3 years ago

  I have been on the keto way of life for 8 months and have seen many positive changes including reversal of gallbladder problems, inflammatory joint pain, debilitating migraines, high blood pressure and insulin resistance. &nbsp;Hoping the benefits also extend to anti-cancer.

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• CA

  @CarcinoJEN · 1 hour ago

  Im 51 and have had cancer since 2016. Im in remission because of metabolic protocols. &nbsp;STG4 mets in 2023. I quit chemo and immunotherapy in april 2024 when stable but not shrinking. A year later I did the press pulse metabolic protocol and was in remission by july 2025. No evidence of disease. Ill share my story. Ill share my scans. Everyone needs to try this BEFORE oncologys dogma gets ya.

• MA

  @MajkaMaria-f9o · 2 days ago

  Super koment &nbsp;vášho hosťa &nbsp;aj vás. &nbsp;Prajem vám obom veľa zdravia a úspechov &nbsp;v práci. Ďakujem &nbsp;❤❤ Mária

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• KE

  @ketomywaymaria8942 · 2 years ago

  Wow, &nbsp;2 hours interview, &nbsp;I have been 15 years learning about nutrition, still learning. &nbsp;❤

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• KA

  @kathleen.d.1231 · 3 years ago

  Keep up this crucial work. Dr Seyfried is awesome.

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• KA

  @Kathleen-usb · 3 years ago

  I love listening to these podcasts but this doctor is way above my understanding.

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• ED

  @edsuriano930 · 3 years ago

  This guy is brillant

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• NE

  @NewLeafHealthChannel · 2 years ago

  My brother is a doctor so mum was bullied into chemo.and radiation 😮 I could see how fast it accelerated the process... She tried but family bullied ❤❤❤

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• CA

  @CarolBaker-c8v · 3 years ago

  I live in Manchester, UK and l&apos;ve recently found these podcasts which l am now addicted too. I love Jesse&apos;s style and his way of asking the most intelligent questions questions. I especially love anything to do with Ketogenic lifestyles and therefore love Dr Thomas Seyfried and this very interesting guest. &nbsp;More please sir and thank you. ❤

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