The Big GLP-1 Debate: What the Science ACTUALLY Says

Comments · 97

• TH

  @TheMetabolicMidwife · 2 months ago

  After over 50 documented diets, exercise programs, Fen-Phen, and an RNY Gastric Bypass all failed, I've lost, not only 280 lbs., but the MASLD, OSA, my CKD has improved from 3B to just under 1, my HFpEF has resolved, my HbA1c has gone from 9.0 to 5.3, and from being immobile for over a decade to now walking 5-7 miles a day. Trulicity for 9 months, then moving to Mounjaro, which I am still on 3+ years later, have saved my life. Over and over again! I went from being 5'1 at 405 lbs. to now being a steady 125 lbs. for 18 months. I've not weighed 125 lbs. since I was 9 years old. I'm 65 now. I laugh when people say those on metabolic medications like GLP-1s are cheating. Hell yeah, I'm cheating! I'm cheating DEATH! I'd never imagined life to be so amazing.

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• AU

  @autumnm2075 · 2 months ago

  My rheumatologist was the doctor who started me on tirzepatide. He had me start the diet changes first, reduction in fat, increasing protein as well as moving more (a stationery bike with side rails, because of fall risk.) I did start losing weight without the medication but it was hard. Once I started my inflammation decreased and my feet stopped hurting slowly my hands and fingers started looking normal, I could move more easily and the weight came off easier. My IBS improved and my last colonoscopy, my 3rd with this doctor, was so good, with no inflammation, that he said I could see him in 10 years. I'm in my 40s and I was anticipating not living into my 80s because of my rheumatologic conditions. Now I get to plan to live longer and spend time with my husband and family, this has changed the way I interact with them. Since I have been on this journey; my husband and one son have told me that they were worried about how long I would live because of the obesity and other health concerns. Tirzepatide has changed my life.

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• KI

  @KimK9394 · 2 months ago

  This was amazing. Thank you so much. I started Zepbound February 2025 and have lost 113 pounds...40% of my body weight. I am. 56 and remember being on a diet when I was 8 years old. Absolutely life changing ❤

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• RY

  @RYBluehorseshoe44 · 2 months ago

  Excellent interview and information sharing. Well done.

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• VA

  @valeriem.9262 · 2 months ago

  This is such solid information! Learning so much here and I appreciate all the open discussions, scientific backgrounds and research, and  Q/A's. Thank you for taking time to present this for the community!! :)

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• JO

  @joanneplante7883 · 1 month ago

  I don't understand how you can naturally stop eating. 😢 Trizepitide has been a lot of help.

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• FE

  @feekeefkd · 2 months ago

  This episode needs to reach more viewers

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• ZE

  @Zepbounded · 2 months ago

  Excellent interview. Articulate, informative, motivational.  -Daniel (Oregon)

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• RE

  @reetayoung · 2 months ago

  Great episode. I love this doctor. I'm taking Mounjaro. I've lost weight, my back pain is gone, I got off of bp med and my kidney function, blood sugar and cholesterol have all improved. I've been on it 4 months.

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• SH

  @shellyolverson1927 · 1 month ago

  I started 2 weeks ago. What this has done for my joint pain is miraculous. I'm taking for obesity.

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• SC

  @ScienceandSelfwithHolly · 2 months ago

  Amazing episode. Love a collab with some of my fave evidence-based creators!

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• JO

  @joanneplante7883 · 1 month ago

  Cool, so good to hear he did a bodybuilding show through Eric Helm 🎉❤

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