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Ranking Isaac's WORST Items

84K views · Sep 28, 2026 · Gaming

Comments · 272

  • @carpet__aisjsjskapajsiasosn · 2 days ago

    The real worst item is the one in your first treasure room

    422

  • @PythonzFire · 2 days ago

    7/10 "FELLAS!" Concept is interesting as an idea but is very limited in its ability to be utilized well. The head on the hands is quite funny though, overall best execution possible given the concept. Not a bad concept, just a limited one.

    343

  • @josephmay852 · 1 day ago

    Adrenaline's biggest use is just making it easier to get SPUN

    89

  • @bengad1606 · 2 days ago (edited)

    Isaac's heart not even being in the honorable mentions is crazy

    137

  • @dapper-alcremie460 · 2 days ago

    I’m prepared for the trademarked bad anothermatt takes

    53

  • @sk8rb0i76 · 1 day ago (edited)

    additional note on plum flute: she spits SO many tears.  it's so easy to get hit because you literally couldn't see past the tear barrage

    25

  • @Lonslo · 1 day ago

    I&apos;m at a loss for words with Samson&apos;s chain<br>I was hyped after the fellas<br>and left the video feeling hollow inside

    33

  • @Craiguuu · 2 days ago

    I unironically watch anothermatt Isaac tier list videos before I go to sleep so thank you for this post :_PlumOMEGALUL:

    56

  • @wargrass0124 · 1 day ago

    I have gotten Clicker to be actually useful for non-mark reasons one single time in thousands of hours, and that’s when I died while having gulped missing poster, and then used Clicker to get into an easier character. And even then, I’m pretty sure it just made me Blue Baby with half a soul heart, so if anything just sticking with The Lost would’ve been easier.

    20

  • @stansmith7438 · 2 days ago

    Just Fellas.

    29

  • @Fluurryy42 · 1 day ago

    ranking worst items one isaac’s birthday is truly another matt moment

    9

  • @Koczel_ · 2 days ago

    Yooo, that was my FELLAS idea from a donate on a stream like a month ago<br>Its cool you used it :D

    18

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