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What is causing the current diabetes epidemic? | Dr. Ralph DeFronzo

46K views · Feb 27, 2025 · Science & Technology

Comments · 213

  • @quengmingmeow · 1 year ago

    This question about “what’s causing the obesity epidemic” drives me nuts. &nbsp;Sure, it’s multi-faceted, but primary to everything is THE FOOD. &nbsp;Today we have super tasty, calorie dense food that is engineered to be as cheap as possible AND designed to leave us less satiated. &nbsp;That’s the primary cause, full stop. &nbsp;This stuff was unavailable to consume 40 years ago. &nbsp;Food is designed today to trigger all the dopamine the brain can handle, and most of us succumb to the temptation. &nbsp;I have not eaten fast food from McDonald’s, Burger King, or Wendy’s in almost 20 years, but guess what…..when I drive by one of those places and smell the aroma coming from the building, I immediately desire it. &nbsp;That’s how strong this addictive power is….and I feel like I have more willpower than most. &nbsp;Food designers have been able to defeat the majority of human willpower….and when it’s cheaper to eat like crap (and a lot of it) as opposed to eating better and more expensive, the war is lost before we even try to fight. &nbsp;<br><br>What’s the solution? &nbsp;I don’t know, but until the population realizes that this is dangerous like any other addiction, we’re just going to put band aids on the problem.

    50

  • @margaretcampbell2681 · 1 year ago

    Along with food, it’s the stress and anxiety

    5

  • @cyc00000 · 1 year ago

    Pete, also thanks for not talking over your guests like you usually do. More conducted like this would be great please!

    7

  • @EngineersRUs · 1 year ago

    It&apos;s also the Aspartame in Diet Coke, Diet Pepsi, Diet Dr. Pepper. &nbsp;Just do an internet search on &nbsp;aspartame and insulin resistance.

    4

  • @leoe.r.7338 · 1 year ago

    I would encourage everyone to listen to the entire interview.

    21

  • @eduardomurillo9305 · 1 year ago

    I&apos;m concerned about the top comments trying to over simplify this without even watching the video. He clearly explains how there can be defects in insulin signaling especially in Hispanics. So it&apos;s not just about eating &quot;healthy&quot; and exercising. I myself take berbarine in addition to a healthy lifestyle to keep my levels in check

    2

  • @kates5994 · 1 year ago

    This was a great podcast. Many thanks learnt a lot.

    2

  • @kathrynsloan4694 · 1 year ago

    I think it is way more complicated than just lack of exercise or eating sugar

  • @peterwilden2162 · 1 year ago

    I was one of the co-authors on Dr. Sun&apos;s Nature paper from Morris White and Ron Kahn lab identifying IRS-1. It is a central player in insulin resistance in insulin sensitive tissues.

    2

  • @bingoberra18 · 1 year ago

    How much does it matter if youre born to younger or older parents? I belive the average age of people having children is increasing, and thereby also some issues.

    4

  • @leeyost9917 · 1 year ago (edited)

    Could be plastics and chemicals clogging liver among other things.ever since bottled water and all the plastics people have been getting the belly fat.

  • @Viv8ldi · 1 year ago

    Where is the full video🥺

    2

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