310 - The relationship between testosterone and prostate cancer, TRT, and more

Comments · 75

• PE

  @PeterAttiaMD · 2 years ago (edited) · pinned

  In this episode, we discuss: <br><a href="https://www.youtube.com/watch?v=fiVCsm4dNh0&amp;t=82">0:01:22</a> - Background on the TRAVERSE trial: insights into exogenous testosterone and prostate cancer risk <br><a href="https://www.youtube.com/watch?v=fiVCsm4dNh0&amp;t=590">0:09:50</a> - The androgen receptor saturation theory: how different organs respond to varying levels of testosterone <br><a href="https://www.youtube.com/watch?v=fiVCsm4dNh0&amp;t=975">0:16:15</a> - The relationship between testosterone levels and prostate cancer aggressiveness: how aggressive prostate tumors have lower androgen receptor activity and rely on different growth mechanisms <br><a href="https://www.youtube.com/watch?v=fiVCsm4dNh0&amp;t=1484">0:24:44</a> - Using the Decipher score to assess prostate cancer aggressiveness and guide personalized treatment strategies <br><a href="https://www.youtube.com/watch?v=fiVCsm4dNh0&amp;t=1992">0:33:12</a> - Considerations for testosterone replacement therapy: how Ted counsels patients, how TRT can be safely administered in patients with low-grade prostate cancer, and more <br><a href="https://www.youtube.com/watch?v=fiVCsm4dNh0&amp;t=2497">0:41:37</a> - Advancements in prostate cancer therapies and PSA as a biomarker for precise treatment decisions, minimizing the need for broad androgen deprivation therapy

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• MI

  @michaelmurphy7983 · 2 years ago

  I’m age 61 and was on TRT for about 4 years before a Gleason 6 diagnosis. &nbsp;I was immediately taken off TRT and am on active surveillance. &nbsp;I’ve had two PSA tests since the diagnosis about 9 months ago. &nbsp;Both times my PSA dropped (currently 4.5). &nbsp;I’ve asked two different Urologists to place me back on TRT since I’m suffering from brain fog, depression (family doc put me on Wellbutrin which has done nothing for me), losing muscle mass, etc. &nbsp;but they refuse. &nbsp;Since I’m on active surveillance, I agree with this doc that I can resume my TRT to get my quality of life back while watching my prostate cancer. &nbsp;I’m so grateful to find a doc who shares my perspective on this!!! It gives me hope that I can find a doc who will write me a script for TRT before I lose my marriage and business due to me not being the real me.

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• LI

  @LibertyandFaith · 8 months ago

  I&apos;ve been taking a TRT for 21 years through a care of a urologist. &nbsp;Initially, when tested, I was told my T level was zero. I currently maintain a level of 700, =/- 100 with weekly injections. &nbsp;My last PSA was 3.1, I am 66 years old and in very good health, exercise daily mixing weights and cardio. &nbsp;Sorry Doctors but this was way over my head. &nbsp;I don&apos;t believe I am at risk for prostate cancer.

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• JE

  @jeffkrosky7259 · 1 year ago

  Dr. Attia, thank you for your pod cast.<br>I have prostate cancer. All good after prostatectomy .<br> My grandson has been diagnosed with Autism bucket 1<br> Your conversations with experts Sutcliff and Schaffer have been very helpful to me. Thank you<br>Jeff

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• LI

  @lindablankenship3856 · 2 years ago

  Great info and really appreciate the mini-Drive format. Please do more of these shorter episodes

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• PR

  @professionalsalonsolutions8608 · 2 years ago

  1 of your best ever. Perfect question and answer and details that has ever been done!

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• PA

  @paulshearer9140 · 1 year ago

  Great interview thanks

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• SK

  @skinfiddler · 2 years ago

  I&apos;m a 72 yo who underwent Brachytherapy for prostate cancer. &nbsp;I was previously on testosterone for two years and felt so much better! &nbsp;At my first PSA check in June my PSA was 0.23 . &nbsp;I was told that after another low PSA test, I&apos;ll be able to return to TRT.

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• ST

  @stephencurry1766 · 1 year ago

  Awesome discussions as ever, thanks guys

• HE

  @HealthDoc · 2 years ago

  I’m a 75 year old white male who had a testicle removed at age 28 (undecended at birth but only discovered and relocated to the scrotum age 8. When I had a vasectomy it was diagnosed as vestigial with cancer risk and removed). My testosterone level was about 400 at age 60. At age 70 I began injecting exogenous testosterone, Sustanon 250 mg/ml every two weeks. This formula combines four esters with different bioavailability so the serum level is made more constant. I now sit at 850 and feel that I have been able to maintain weight, musculature and fitness levels I surly would have lost without supplementation (6’ 165) I had BPH with a PSA of 14 age 50. Biopsy revealed no cancer but was followed with a TURP. Both of my parents lived to age 92. I feel I made the right choice to push back against nature and extend my vitality.

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• JI

  @JimmyStatic · 2 years ago

  I’d love to see a discussion of hCG monotherapy.

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• PA

  @parnellmarketing · 1 year ago

  I took testosterone injections for 4 years. &nbsp;I got prostate cancer. &nbsp;I had a robotic prostatectomy. &nbsp;Dr’s say the cancer was contained. &nbsp;Should I get back on Testosterone now? &nbsp;My energy sucks!

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