Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113

Comments · 805

• LE

  @lexfridman · 6 years ago · pinned

  I really enjoyed this conversation with Manolis. Here&apos;s the outline:<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU">0:00</a> - Introduction<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=234">3:54</a> - Human genome<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=1067">17:47</a> - Sources of knowledge<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=1755">29:15</a> - Free will<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=2006">33:26</a> - Simulation<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=2117">35:17</a> - Biological and computing<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=3010">50:10</a> - Genome-wide evolutionary signatures<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=3414">56:54</a> - Evolution of COVID-19<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=3779">1:02:59</a> - Are viruses intelligent?<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=4328">1:12:08</a> - Humans vs viruses<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=4779">1:19:39</a> - Engineered pandemics<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=5003">1:23:23</a> - Immune system<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=5602">1:33:22</a> - Placebo effect<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=5739">1:35:39</a> - Human genome source code<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=6280">1:44:40</a> - Mutation<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=6706">1:51:46</a> - Deep learning<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=7088">1:58:08</a> - Neuralink<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=7627">2:07:07</a> - Language<br><a href="https://www.youtube.com/watch?v=brslF-Cy3HU&amp;t=8119">2:15:19</a> - Meaning of life

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• BR

  @BrianLKL222 · 6 years ago

  &quot;We are not the inventors of the first digital computer, we are the descendants of the first digital computer&quot;<br>this introduction gave me goosebumps...

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• YA

  @yashkarbhari721 · 6 years ago

  Nobody:<br><br>Lex Fridman: &quot;Sorry for romanticizing the question &quot;

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• NE

  @Nexus2Eden · 6 years ago

  The only thing I am upset about is that every single podcast blows my mind! I keep putting it on, thinking &quot;Oh I&apos;ll just listen to this in the background.&quot; And then spend 2 hours and 30 minutes glued to the screen say, &quot;Yes! Yes! Exactly! YES!&quot; And feeling like I want to move to the island where all you and your guests live and we all work together to build and amazing world. I cannot adequately share the level of respect, humility, gratitude, and inspiration your podcast has for me and I&apos;m sure millions in the future. Such an amazing gift - better than anything I&apos;ve ever gotten for Christmas! or my Birthday! Ever! Absolutely life affirming! Love you Lex - &nbsp;keep knocking it out of the park. And Manolis...I can&apos;t even! Brilliant! What a exceptional human being. Wow! Thanks again Lex! The best ever! You are the Science Guy&apos;s Joe Rogan!

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• RO

  @rogerzen8696 · 5 years ago

  I am a 49 yr old business owner. Listening to Lex&apos;s podcasts made me enroll in MIT&apos;s Data Science degree program to study AI, listening to these Manolis episodes made me take up computational biology courses. Absolutely fascinating!

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• NE

  @nepaalidude · 6 years ago

  this is what getting high on life actually and literally means.

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• ZU

  @zuhairmehdee · 6 years ago

  I loved this episode. Manolis Kellis clearly loves his work and he&apos;s great at spreading that excitement.

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• TI

  @timgrove3927 · 6 years ago

  One of the best interviews Lex has done I think.

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• CH

  @chickenshieee · 6 years ago

  You’re the Joe Rogan of science Lex

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• ZA

  @ZacheryGlass · 6 years ago

  When Sam Harris stopped talking about interesting scientific topics, this became my favorite podcast

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• RU

  @russelltreadway · 6 years ago

  The last minutes made me cry, as a father I really appreciate his wisdom. Thank you.

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• ST

  @star-302 · 6 years ago

  Manolis was soo good that he created a system overload in Lex&apos;s brain.

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