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55: Uric Acid with Dr. Ben Bikman

295K views · May 15, 2024 · Science & Technology

Comments · 950

  • @jamesgordon8867 · 2 years ago

    Why don't we have more professors like this gifted educator?

    388

  • @jamesgordon8867 · 2 years ago

    Dr. Bikman,<br>If this is how you talk to your kids, they are truly blessed! Your heart comes out when you talk! Thank you, sir, for teaching outside the classroom! We need your lectures!

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  • @jamesgordon8867 · 2 years ago

    &quot;Why we get sick &quot; should be in every doctor&apos;s office: waiting room &amp; exam room

    86

  • @thomasarcher4034 · 2 years ago

    Thank you for not focusing on gout. &nbsp;I&apos;ve had gout. &nbsp;Although painful I doubt many people have died from it. &nbsp;In reality, gout is a blessing in that it should alert you to hyperuricemia and the possibility of uric acid crystals elsewhere. &nbsp;We may become aware of gout with a joint hurting but uric acid crystals have been found many places-- in coronary arteries, aorta, heart valves, myocardium, kidneys, prostate, and pancreas amongst others. &nbsp;Crystals have even been found in atherosclerotic plaques. &nbsp;Its frequency is VERY underappreciated because it&apos;s hard to detect. &nbsp;Routine tissue fixation with formalin washes out uric acid crystals. &nbsp;Likewise, tissue is usually cut 7 microns thick for microscopy. &nbsp;Uric acid crystals are usually linear and, if they&apos;re perpendicular to the slide, will appear as a small dot. &nbsp;To see uric acid crystals one has to preserve the tissue with methanol, not formalin. &nbsp;Following this, special lighting is required to see the crystals. &nbsp;Studies which have employed this method have shown crystals to be far more extensive than the joints. &nbsp;I can&apos;t imagine that uric acid crystals in the coronary arteries initiating an inflammasome reaction is good. &nbsp;Uric acid crystals don&apos;t show well on routine x-rays and scans. &nbsp;It usually requires a specialized cat scan called dual energy CT (DECT scan). &nbsp;These scans will often show uric acid crystals in the calcium in atherosclerotic plaques.<br><br>Unfortunately gout is treated poorly. &nbsp;Give an anti-inflammatory and if it recurs we&apos;ll &quot;think about&quot; treatment with allopurinol or febuxostat. &nbsp;Hyperuricemia, not JUST uric acid crystals, IS serious. &nbsp;It&apos;s like a criminal whose fingerprints are left behind at many crime scenes- the heart, kidneys, liver, pancreas. &nbsp;The tragedy is that we have good drugs and it&apos;s usually easy to treat. &nbsp;Anyone diagnosed with gout or hyperuricemia should be thoroughly evaluated for heart, liver, and kidney disease. &nbsp;<br><br>For every molecule or uric acid produced there is also a molecule of hydrogen peroxide generated. &nbsp;I&apos;ve often wondered how much pathology is caused by this, as opposed to the uric acid itself.

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  • @krabbend8 · 2 years ago

    I eliminated gout completely by skipping all fructose (fruit &amp; sugar)

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  • @beckysmith1862 · 1 year ago

    I can never get enough of Ben Bikman!

    49

  • @charlotteprout-jones7257 · 2 years ago

    The cause for uric acid must be fructose. &nbsp; Because most carnivores report that arthritis and gout cleared up completely after they went on meat, eggs, water &amp; salt

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  • @sabinealexander2773 · 7 days ago (edited)

    What an excellent presentation 👍 as a gout patient for over 20 years I appreciate such valuable information on &nbsp;the subject. &nbsp;And fructose is ,as the doctor said , &nbsp;the worst enemy for gout sensitive people like me.

    1

  • @fronniebealer7808 · 2 years ago

    The more I listen to these lectures, the easier they are to understand.

    124

  • @lookingatyou1478 · 11 months ago

    What an absolute treasure you are Dr. Bikman.

    6

  • @yvonnekiwior9633 · 2 years ago

    Morning coffee with Ben!!!! My favorite teacher ever🎉<br>Great topics always❤

    69

  • @Andrew-tr5zg · 3 weeks ago (edited)

    Hi Dr Bikman, thank you so much for all that you do and share on here, I&apos;ve watched so many of your classrooms and watch right to the end (which is rare for me to watch more than 5 mins of a you tube video!)<br><br>For the last ten or so years I&apos;ve had many issues with hypertension, a minor stroke and gout (at one point my glucose reading was 8.2!). Through my own research and trainings, such as your content, I&apos;ve been able to bring down a lot of my markers like high glucose (5.6)/Homa-IR due to mainly lifestyle changes/exercise and avoiding fructose as much as I can, my weight has dropped (42 pounds since 2 years ago, still a ways to go however) and other metabolic markers are becoming more normal. <br><br>I do still have high uric acid levels and I believe this is in part to my BP meds as has been hinted at in some studies. I did have to stop bendroflumethiazide a few years back as it was nuking my kidney function. I did think about getting my doc to prescribe allupurinol but really do not want to be on yet another prescription med. I am interested in the research you mentioned about Allulose. I may have missed it but was research for this in the show notes or do you have a link to it? Again, many thanks for all that you do.

    1

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