How the Krebs cycle powers life and death – with Nick Lane
388K views · Aug 4, 2022 · Science & Technology
Comments · 446
@garyk.nedrow8302 · 3 years ago
I studied the Krebs cycle at Brown Univ. in 1960 in the Unicelluar Biology course, which in retrospect was largely devoted to memorizing complex chemical reactions, with very little real understanding of their purpose. Of course, a lifetime of science since then has improved upon our earlier understanding of the cycle. Prof. Lane in this short video not only explains the Krebs cycle with beautiful clarity, but then relates it to my later interest, evolutionary biology, and the anaerobic processes that pioneered the cyclical chemical reactions that made oxygen-based life possible. This video ought to be a mandatory introduction to biochemical processes for biology students to aid in the integration of organic chemistry with life processes and to illustrate the necessity of integrating multi-disciplinary research. Many thanks, Prof. Lane, in simplifying the highly complex workings of the Krebs cycle and its extensive applications.
125
@saminselenciata4861 · 2 years ago
its almost unbelievable that we get to experience this talk for free
19
@holidaynova · 4 years ago
i’m 46 an engineer and physicist, this all finally brought everything together.
21
@gcarletonYou · 4 years ago
As a sense of how I feel about him and his articulation of microbiology, read his past books but also got audible and book Transformer. I have gone through that material twice, amazed how much new thoughts in rereading, third time will likely be the same. Yet I also found this lecture to be incredible, he takes science to the realm of philosophy of life, but in context of science. His reference to past scientists is appreciated, and he does so in a humble way, never bragging about himself. Bill Gates endorsement of Nick Lane being one of his favorite authors is deserved. I try to read technical journals to the extent I am able to get past the enormous complexity and vocabulary, but Lane gives me a shot of understanding them. Great video, great man.
165
@spacelemur7955 · 3 years ago
As an interested layman who has always read text books in biology, geology and their subfields for the last 50 years, this was effing exciting! So many concepts nudged closer together. Wow. Simply wow.
10
@AliceYobby · 3 years ago
Took a while for me to understand what he was getting at, but once I did, it truly changed my perspective on what life even is. Pretty powerful stuff
9
@lthammox · 4 years ago
Nick Lane’s such a wonderful thinker and communicator. Really recommend his books. Had the pleasure of meeting him a couple of times, and he’s just the loveliest person.
133
@rumraket38 · 4 years ago
A Nick Lane talk is never boring.
18
@Raydensheraj · 4 years ago
His book "The Vital Question" is still one of the best concerning abiogenesis, mitochondria, deep sea vents, biochemistry etc...<br><br>Definitely one of the classics...and I know that a lot of people highly recommend "The Vital Question"...
35
@smitsun · 3 years ago
It's a pity I cannot upvote this more than once. What a marvelous lecture!
14
@TheDogNannyEdmonton · 2 years ago
I LOVE that all this information is available to the public and those interested in learning! And not only available to those attending University! And SO GRATEFUL for professors such as this who understands it and can bring it to the public! ❤🙏❤
6
@colinhenshaw3737 · 4 years ago
Absolutely brilliant, and a must for any student studying biochemistry. I was particularly fascinated with the involvement of the Krebs Cycle in the evolution of early life, and the Cambrian Explosion.
38
Up next

Nick Lane | The Gifford Lectures: Beyond the Series - Why is Life the way it is?
The University of Edinburgh · 71K views

Vicky Ooi- Thesis Defense: Determining the effects of sex and temporal variation on the late ...
Moss Landing Marine Labs · 87 views

What Is Electricity Made Of According to Quantum Physics?
Sleep On Physics · 317K views

Did Dinosaurs Change How Humans Age?
Past in Paint · 91 views

CAIC Launch - Shaun Nichols | The Injunctive Drive: The Emergence of Norms from Cognitive Biases
Cognition, Agency, and Intelligence Center · 421 views

What if everything you touch is an illusion? | Quantum field theory with David Tong
The Royal Institution · 6.9M views

How Life Works and The Case for a “New Biology” | Philip Ball | CBF TALK 003
Conceptual Biology Forum · 3.2K views

AI Expert WARNS: "You're Not Ready For 2027"
The Diary Of A CEO Clips · 1.1M views

Karl Friston Beyond the Free Energy Principle: A Life Driven by Curiosity
Podcastimus · 50 views

“I find it almost disturbing that the universe favors life this strongly” – Nick Lane
Dwarkesh Patel · 152K views

Revolution by Natural Selection - Professor Nick Lane, University College London
Darwin College Lecture Series · 49K views

What Actually Are Space And Time?
History of the Universe · 12M views

Nick Lane: Origins of Life, Evolution, Alien Life
Curt Jaimungal · 68K views

Mindscape 198 | Nick Lane on Powering Biology
Sean Carroll · 33K views

How Infrared Light Actually Affects Your Mitochondria - Hypothesis
MedCram - Medical Lectures Explained CLEARLY · 67K views

The Mind-Bending Understanding of Time | Prof. Jim Al-Khalil
The Peter McCormack Show · 431K views

What is a Quantum Field Made Of According to Quantum Physics?
Sleep On Physics · 83K views

Fasting Mimicking Diet Cycles - Valter Longo BSRA public lecture 2026
BSRAgeing · 938 views

Trump lays out ‘bonkers’ economic plan as Canada emerges as ‘leaders' of free world | Justin Wolfers
The Trump Report and Platypus Economics with Justin Wolfers · 595K views

Diverse Intelligence: Intrinsic Motivation in Evolved and Engineered Systems | M. Levin | IMOL 2025
IMOL · 515 views